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Transgenic hACE2 mice for SARS-CoV-2 and COVID-19 | Taconic Biosciences
Transgenic hACE2 mice for SARS-CoV-2 and COVID-19 | Taconic Biosciences

A bioengineered pseudovirus nanoparticle displaying SARS‐CoV 2 RBD fully  protects mice from mortality and weight loss caused by SARS‐CoV 2 challenge  - Xia - 2023 - Biotechnology Journal - Wiley Online Library
A bioengineered pseudovirus nanoparticle displaying SARS‐CoV 2 RBD fully protects mice from mortality and weight loss caused by SARS‐CoV 2 challenge - Xia - 2023 - Biotechnology Journal - Wiley Online Library

Molecules | Free Full-Text | K18- and CAG-hACE2 Transgenic Mouse Models and  SARS-CoV-2: Implications for Neurodegeneration Research
Molecules | Free Full-Text | K18- and CAG-hACE2 Transgenic Mouse Models and SARS-CoV-2: Implications for Neurodegeneration Research

Novel transgenic mice with Cre-dependent co-expression of GFP and human  ACE2: a safe tool for study of COVID-19 pathogenesis | Transgenic Research
Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis | Transgenic Research

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by  Neutralizing Antibodies - ScienceDirect
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies - ScienceDirect

JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice  infected with SARS-CoV-2 develop severe and fatal respiratory disease
JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

Brain cross‐protection against SARS‐CoV‐2 variants by a lentiviral vaccine  in new transgenic mice | EMBO Molecular Medicine
Brain cross‐protection against SARS‐CoV‐2 variants by a lentiviral vaccine in new transgenic mice | EMBO Molecular Medicine

Kaplan-Meier curves for K18 hACE2 transgenic mice after SARS-CoV-2... |  Download Scientific Diagram
Kaplan-Meier curves for K18 hACE2 transgenic mice after SARS-CoV-2... | Download Scientific Diagram

Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a  single-dose mucosal immunization with a parainfluenza virus 5–based  COVID-19 vaccine | Science Advances
Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5–based COVID-19 vaccine | Science Advances

Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5 |  Science Advances
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5 | Science Advances

hACE2 transgenic mouse model for coronavirus (COVID-19) research
hACE2 transgenic mouse model for coronavirus (COVID-19) research

Frontiers | Experimental Models of COVID-19
Frontiers | Experimental Models of COVID-19

034860 - K18-hACE2 Strain Details
034860 - K18-hACE2 Strain Details

Mouse model of fatal COVID-19 developed for vaccine and drug testing
Mouse model of fatal COVID-19 developed for vaccine and drug testing

Biotechnology - hACE2 transgenic mouse, animal models for SARS-CoV-2  vaccine- or drug-development (Service provided by A4 Transgenic mouse models  core facility) | National Core Facility for Biopharmaceuticals
Biotechnology - hACE2 transgenic mouse, animal models for SARS-CoV-2 vaccine- or drug-development (Service provided by A4 Transgenic mouse models core facility) | National Core Facility for Biopharmaceuticals

One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice  from SARS-CoV-2 upper and lower respiratory tract infection | PNAS
One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection | PNAS

Frontiers | Heterogeneous Infectivity and Pathogenesis of SARS-CoV-2  Variants Beta, Delta and Omicron in Transgenic K18-hACE2 and Wildtype Mice
Frontiers | Heterogeneous Infectivity and Pathogenesis of SARS-CoV-2 Variants Beta, Delta and Omicron in Transgenic K18-hACE2 and Wildtype Mice

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta  SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice | Journal of  Virology
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice | Journal of Virology

Age associated susceptibility to SARS-CoV-2 infection in the K18-hACE2  transgenic mouse model | GeroScience
Age associated susceptibility to SARS-CoV-2 infection in the K18-hACE2 transgenic mouse model | GeroScience

SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary  disease in COVID-19 | Cellular & Molecular Immunology
SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19 | Cellular & Molecular Immunology

SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2  Knock-In Mice | Journal of Virology
SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice | Journal of Virology

Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human  Angiotensin-Converting Enzyme 2 - ScienceDirect
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 - ScienceDirect

Diet induced obesity and type 2 diabetes drives exacerbated sex-associated  disease profiles in K18-hACE2-mice challenged with SARS-CoV-2 | bioRxiv
Diet induced obesity and type 2 diabetes drives exacerbated sex-associated disease profiles in K18-hACE2-mice challenged with SARS-CoV-2 | bioRxiv

A longitudinal molecular and cellular lung atlas of lethal SARS-CoV-2  infection in K18-hACE2 transgenic mice - eBioMedicine
A longitudinal molecular and cellular lung atlas of lethal SARS-CoV-2 infection in K18-hACE2 transgenic mice - eBioMedicine